OVERVIEW:

The current era demands extensive effort to cope up with the challenges of the advancing world and this can lead to un-healthy lifestyle and sleep problems. Extensive sitting hours and lack of sleep due to work pressure can lead to stress, anxiety, agitation, and insomnia. Every individual has experienced it at some point of their life. The following article is regarding a drug that can help cure such conditions.  

SLEEPING PILLS:

Sleeping pills UK has gained immense popularity in the recent decades to help individuals have sound sleep to improve their overall performance and body functioning. Insomnia has become one of the leading causes of distress among the working population. Sleeping pills can offer short-term relief but one should focus on the root cause.

RIVOTRIL:

Rivotril is one of the medicines used for inducing sleep and belongs to the classification of benzodiazepines and people buy Rivotril 2mg to improve the quality of sleep.

INDICATIONS FOR USAGE:

Rivotril medicine has a wide range of applications such as:

1. Used as a sleeping aid in patients of insomnia.
2. To treat seizures, especially for epilepsy in infants and children.
3. Status epilepticus (prolong or repeated epileptic attack).
4. To help patients with panic disorders.
5. To relieve anxiety levels among anxious individuals.
6. Very effective among individuals suffering from movement disorders such as akathisia.

MECHANISM OF ACTION OF RIVOTRIL:

The basic mechanism of action of Rivotril is that it acts on the central nervous system and helps in increasing the levels of a calming neurotransmitter known as GABA (gamma-aminobutyric acid). An increase in GABA levels helps in the following ways:

1. Relieves anxiety
2. Prevents seizures
3. Reduces episodes of awakening from REM disorders
4. Relaxes tense muscles
5. Helps in inducing deeper state of sleep.

AVAILABLE FORMS OF RIVOTRIL:

As Rivotril addresses a wide range of age groups and also different forms of disease type. Hence, it is also available in different forms to suit each type of individual starting from infants to children and adults. Its availability is in the following forms:

• Tablet or pills
• Injections
• Drops 

RECOMMENDED DOSAGE OF RIVOTRIL:

Rivotril comes in multiple strength forms, such as 0.5 milligrams and Rivotril 2mg. different strengths have different implications and a variety of strength form can allow you to split the dosage in increments to give body enough time to accept the drug. 

· ADULT DOSAGE:

Adult starting dosage should not exceed 1.5 milligrams in a day in divided form, it will allow the body to get tuned with the drug with minimum side effects. However, the maintenance dose for a healthy adult should be 8 milligrams to 10 milligrams per day in 3 divided doses.

· CHILDREN DOSE:

The dosage is calculated as per the body weight among the children till 10 years of age or who are less than 30 kilograms in weight. 0.01 to 0.03 milligrams are the recommended dosage per kilogram of body weight. The maximum dose per kilogram should not exceed 0.05 milligram per kg body weight and the maintenance dose ranges between 0.1 to 0.2 mg per kilogram of body weight.

GUIDELINE TO ACHIEVE MAXIMUM RESULTS:

There is always a set pattern to take a medicine and adhering to the doctor’s advice is the key to success, following are some of the guidelines that one should follow when one is taking rivotril:

1. One should strictly follow the dosage pattern given by the doctor.
2. In case of a missed dose take it as you remember missing it.
3. If the time for next dosage comes then skip the missed dose and consult the doctor for further advice.
4. Never take a double dose in order to compensate for the missed dose.
5. It can be taken on an empty stomach or with food.
6. Grape fruit juice should be avoided as it can increase the level of drug in the blood.
7. The dose should be divided in to increments to minimize adverse effects.
8. It should be taken almost an hour before going to bed.
9. It should only be taken when one is planning to sleep at a stretch of almost 6 to 8 hours.
10. A proper diet and sleep schedule should be followed to help body have a set sleep pattern.
11. Alcohol intoxication should be avoided.

CONTRAINDICATIONS:

The drug is contraindicated under the following circumstances and should be avoided to eliminate any life-threatening consequences:

1. If one is allergic to rivotril altogether or any specific ingredient of the medicine.
2. If allergic to any other benzodiazepine, then it should also be avoided.
3. Myasthenia gravis
4. Severely compromised liver such as end stage liver failure.
5. Acute glaucoma
6. Closed-angle glaucoma
7. Sleep apnea
8. Breathing difficulties 

ADVERSE EFFECTS:

Like all other drugs rivotril also has its share of side effects such as:

• Slow psychomotor function
• Dizziness
• Drowsiness
• Lack of focus
• Saliva drooling due to increased watering of oral cavity
• Fatigue
• Muscular weakness
• Dis-orientation
• Aggressiveness and agitation
• Nervousness
• State of confusion
• Appearance of new seizures
• Increased frequency of seizures
• Unexplained cough
• Hallucinations
• Loss of balance resulting in repeated falls
• Short term memory loss
• Depression
• Nightmares
• Trouble sleeping
• Nausea
• Vomiting
• Diarrhea
• Weight loss
• Loss of appetite
• Dark urine
• Pale stools
• Yellowish discoloration of skin and the cornea of eye
• Thoughts of self-harm or suicidal thoughts
• Slurred speech
• Low blood pressure
• Uncontrolled eye movements
• Drug dependence

The incidence of occurrence of these side effects is very low almost 1% of the population has reported regarding the side effects. The side effects are quite manageable and almost all tapper off after some time. In case of any life-threatening sign or symptoms such as severe allergic reaction, difficulty in breathing or too much sleepiness pharmacist or the physician should be promptly consulted to avoid